Commentary: Change will not happen overnight

The HCV Revolution Did Not Happen Overnight

The progress in HCV therapy in the last three years is similar to the progress that took HIV therapy ∼14 years. We are at the brink of approval for an all-oral drug combination that is dosed once daily as a single pill, has >95% efficacy, and is well tolerated. This article summarizes the path to this success and the challenges still ahead.

What Will Probably Happen

3. Accidents Will Happen

Few students of the subject of intoxicants and traffic safety now doubt that marijuana, like alcohol, can exert detrimental influence. Just how detrimental is debatable. The debate pits optimists ("it's much less of a problem than alcohol") versus those on the pessimistic side ("but who needs any new problems?"). Yet there can be no question that some drivers who met their ends on the highway w...

It Will Happen to You

Everyone experiences bereavement but few give prior thought to it. Knowing something about the possible reactions and repercussions of bereavement is the best preparation for it.

What Will Happen to Brazilian Fertility?

Despite the absence of an official family planning policy, demographic changes in Brazil occurred at an unprecedented pace in the second half of the twentieth century, ushering in an era with total fertility rates near the replacement level. According to the population censuses, the total population in Brazil was 52 million in 1950 and 170 million in 2000. This reflected a mean annual growth ra...